Total 21 article(s)

   국가연구개발 우수성과 100선 선정 / admin


국가연구개발 우수성과 100선 선정

화학과 심윤보 교수가 ‘2017 국가연구개발 우수성과 100선’에 선정됐다.

과학기술정보통신부가 선정하는 ‘국가연구개발 우수성과 100선’은 과학기술에 대한 이해와 자긍심을 높이고자 2006년부터 선정·발표되고 있다.
올해는 정부 지원을 받아 수행한 연구개발과제 총 5만 4천여 건 중 후보과제 추천과 전문가 선정위원회 심사를 거쳐 최종 100개 과제가 선정됐다.

이 중 심윤보 교수는 과학기술정보통신부의 지원을 받아 추진한 ‘전기화학적 전위 변조 마이크로플루이딕 디바이스 개발 및 채널 전극 재료 축조
기술 기반의 응용에 대한 연구’로 우수성과를 도출해 100선에 포함됐다.

우수성과로 선정된 과제는 해당사업과 기관 평가에서 가점이 부여되며, 해당 연구자는 신규 연구개발(R&D) 과제 선정 시 우대를 받을 수 있다.

이번 우수성과 선정 결과는 핵심 기술의 내용, 해당기술의 파급효과, 연구 후일담 등과 함께 사례집으로 발간돼 국회 및 공공기관과 주요 도서관,
연구기관에 배포될 예정이다. 국가과학기술지식정보서비스(NTIS, www.ntis.go.kr)의 ‘우수성과’ 코너에서도 열람이 가능하다.


PNU 포커스 - 뉴스


   70세까지 정년 연장 「석학교수」… 심윤보 교수 등 5명 첫 임용 / admin


부산대가 우수 교원의 강의시수 부담을 줄여주고 만65세인 정년을 만70세까지로 5년간 연장해주는 새로운 「석학교수제」를 도입해 화학과 심윤보 교수와
기계공학부 강충길 교수, 화학공학·고분자공학과 박대원 교수·하창식 교수, 약학부 이복률 교수 등 5명을 3월 1일자로 첫 석학교수에 임용했다.
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부산대소식 제 832호


   후속 도약 과제 선정 (2015.09.01 ~ 2018.08.31) / admin


젼위변조 마이크로채널의 개발 및 전기화학적 분리분석법연구

   hispanicbusiness 홈페이지에 기사 게재됨 / admin



   Electroanalysis Associate Editor / 관리자


Electroanalisys, WILEY-VCH associate editor

   Global medical discovery에 "Key Scientific Articles" 로 소개됨. / 관리자


Ultrasensitive and selective electrochemical diagnosis of breast cancer based on a hydrazine-Au nanoparticle-aptamer bioconjugate.

Zhu Y, Chandra P, Shim YB.

Anal Chem. 2013 Jan 15;85(2):1058-64.

Department of Chemistry and Institute of Bio-Physico Sensor Technology, Pusan National University, Busan 609-735, South Korea.

 

Abstract

Human epidermal growth factor receptor 2 (HER2) and HER2-overexpressing breast cancer cells were detected using an electrochemical immunosensor combined with hydrazine and aptamer-conjugated gold nanoparticles (AuNPs). The sensor probe was fabricated by covalently immobilizing anti-HER2 onto a nanocomposite layer that was composed of self-assembled 2,5-bis(2-thienyl)-1H-pyrrole-1-(p-benzoic acid) (DPB) on AuNPs. The hydrazine-AuNP-aptamer bioconjugate, where the hydrazine reductant was directly attached onto AuNPs to avoid the nonspecific deposition of silver on the sensor surface, was designed and used to reduce silver ion for signal amplification selectively. The silver-stained target cells were visualized easily by the bare eye and an optical microscope, and the cells were quantitatively analyzed using stripping voltammetry. The parameters affecting the analytical response were optimized. The proposed sensor was capable of differentiating between HER2-positive breast cancer cells and HER2-negative cells. This method exhibited an excellent diagnosis method for the ultrasensitive detection of SK-BR-3 breast cancer cells in human serum samples with a detection limit of 26 cells/mL.


Global medical discovery

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   ChemComm 표지논문으로 소개 및 영국의 Chemmistry World 잡지에 소개 / 관리자


ChemComm 표지논문

Chemmistry World 잡지의 기사소개


   새로운 Cancer Cell Detection 방법으로 RCS(Royal Society of Chemistry)에 "Hot" article로 소개됨 / 관리자


A new way to look at cancer cell detection

14 Jan 2013

Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

A novel cancer cell detection method, based on the interaction between daunomycin (DAN – an anticancer drug used in chemotherapy) and cell membrane components, has been developed by scientists in South Korea.

The method uses the electrochemical and fluorescence behaviour of DAN and uses an aptamer probe immobilised on a conducting polymer-gold nanoparticle composite film.

he aptamer sensor probes using electrochemical impedance spectroscopy and fluorescence microscopy. The method differentiates between cancerous and non-cancerous cells at low concentrations (0.01μM).

Read the ‘HOT’ Communication in full:

Cancer cell detection based on the interaction between an anticancer drug and cell membrane components
Pranjal Chandra , Hui-Bog Noh and Yoon-Bo Shim
Chem. Commun., 2013, DOI: 10.1039/C2CC38235K




   Cu-Co alloy dendrite의 활용에 대한 연구가 "Renewable Energy Global Innovations"에 소개됨 / 관리자








Application of a Cu–Co alloy dendrite on glucose and hydrogen peroxide sensors



Hui-Bog Noh, Kyung-Sun Lee, Pranjal Chandra, Mi-Sook Won, Yoon-Bo Shim

Electrochimica Acta, Volume 61, February 2012

Abstract


A Cu-Co alloy dendrite with a hierarchical nanostructure was electrochemically synthesized, and it characterized using scanning electron microscope, energy dispersive X-ray spectroscopy, time-of-flight secondary ion mass spectrometry (TOF-SIMS), X-ray diffractometery, X-ray photoelectron spectroscopy, coulometry, and cyclic voltammetry. The catalytic characteristics of the dendrite were examined for its use with highly sensitive glucose and H2O2 sensors. The TOF-SIMS image shows that the Cu-Co alloy dendrite grew homogeneously in a hierarchical structure. The Co2+ ions that formed on the alloy dendrite mainly contributed to glucose oxidation, and the Cu+ ion cooperated synergically with the Co2+ ion. However, Co3+ was mainly involved in the reduction of H2O2, while the reduction with Cu2+ ion cooperated synergically. The major oxidation products of glucose on the dendrite was confirmed to be formate (12-electron oxidation product) through coulometry and product analysis with a HPLC-MS analyzer. The linear calibration plots for the glucose and H2O2 analyses were obtained between 0.5 μM – 14.0 mM (detection limit was 0.10 ± 0.05 μM) and 1.0 μM – 11.0 mM (detection limit was 0.75 ± 0.15 μM), respectively. The performance of the final sensor was evaluated with a human blood sample.


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   전도성 고분자(Conductive Polymers)에 대한 연구로 AZoM.com(The A to Z of Materials)에 Thought Leaders 로 소개 / 관리자


AZoM.com : The A to Z of Materials에 의해서 Thought Leaders 로 소개

Thought Leaders Invitation for AZoM.com
The A to Z of Materials : Materials Thought Leaders


Conductive Polymers: Applications for Electronic Devices and Sensors

Yoon-Bo Shim, Professor, Department of Chemistry and Director, Institute of BioPhysio Sensor Technology, Pusan National University, South Korea. Corresponding author: ybshim@pusan.ac.kr

Conductive polymers have seen great advancement during the last two decades. In general a half filled valence band, formed from a continuous delocalized π –system, is an ideal condition for conduction of electricity. However, a π –conjugated polymer can lower its energy more efficiently by bond alteration (alternating single and double bonds) and can introduce a band width of 1.5 eV making it a high energy gap semiconductor.

Conducting polymers are extensively studied due to their remarkable electronic properties such as electrical conductivity, low energy optical transitions, low ionization potential, and high electron affinity. Their fundamental spectroelectrochemistry, and the applications to solar cells, biosensors, and biofuelcells have been extensively explored by our laboratory during the last decade. Some important contributions are highlighted below.